AePVIII_Skesters

Skesters, Andrejs – Kustovs, Dmitrijs – Lece, Anna,
Scientific Laboratory of Biochemistry, Institute of Occupational Safety and Environmental Health of Riga, Stradiņš University, Riga, Latvia

Impact of Pelargonium Sidoides on Periodontal Inflammation and Improvement of Oral Health
DOI: https://doi.org/10.71067/AePVIII-2022-143-155  
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Aegyptus et Pannonia VIII, Acta Symposii anno 2021, Plants and Health from Ancient Egypt. to the Present Day.
Proceedings of the Conference held between 14th and 16th October 2021, Budapest; ed. by Hedvig Győry.
Published by The Ancient Egyptian Committee of the Hungarian-Egyptian Friendship Society, Budapest 2022.
ISBN: 978-615-6571-02-1; DOI: https://doi.org/10.71067/AePVIII-2022  
Soft cover. No Jacket. 1.st Edition. 6+348 pages (24x17), with colour pictures.

Abstract:
The current study inspects the antioxidant capacity of Pelargonium sidoides DC. crudum root extract (PSRE) and proanthocyanidins isolated f    rom Pelargonium sidoides root extract (PACN) for periodontal disease. A total of 77 subjects with periodontitis were enrolled in this study. Oxidative damage to lipids (MDA Adduct, enzymatic antioxidant Cu, Zn-Superoxide Dismutase (Cu, Zn- SOD) activity and Total Antioxidant Status (TAS) were detected in saliva before and after treatment with PSRE or PACN gum chips in different formulations. The initial antioxidant status of periodontal patients’ saliva is characterized by increased concentration of MDA Adduct, TAS and Cu, Zn-SOD. After 3 months of treatment MDA Adduct level decreased using only Ferentis PSRE and PACN gum chips, Cu, Zn-SOD activity decreased in all formulation groups, while TAS
remained unchanged. In conclusion, Ferentis PSRE, and PACN gum chips possess antioxidant properties and are suggested as additional support for treatment of the periodontal disease.